| | Runs | playerId | seasonId | clubId | matchId | Runs | Player | Team | Season | Grade | Round | Inns | Opponent |
| 1 | 125 | 676844 | 155 | 268 | 3958790 | 125 | John H Anderson | Northern District | 2021/2022 | Second Grade | 2 | 1 | UNSW |
| 2 | 120 | 676843 | 155 | 268 | 3958798 | 120* | Daniel A Anderson | Northern District | 2021/2022 | Second Grade | 3 | 1 | Hawkesbury |
| 3 | 117 | 661271 | 155 | 268 | 3957559 | 117 | Scott A Rodgie | Northern District | 2021/2022 | First Grade | 6 | 1 | Blacktown Mounties |
| 4 | 111 | 661271 | 155 | 268 | 3957671 | 111* | Scott A Rodgie | Northern District | 2021/2022 | First Grade | 9 | 1 | Mosman |
| 5 | 109 | 879100 | 155 | 268 | 4008913 | 109* | Sam C Weir | Northern District | 2021/2022 | AW Green Shield | 3 | 1 | Parramatta |
| 6 | 104 | 1247723 | 155 | 268 | 3963817 | 104 | Avinash L Mirando | Northern District | 2021/2022 | Fifth Grade | 3 | 1 | Hawkesbury |
| 7 | 102 | 1610778 | 155 | 268 | 3995456 | 102 | Mia J Cook | Northern District | 2021/2022 | U18 Brewer Shield | 5 | 1 | Universities |
| 8 | 91 | 879100 | 155 | 268 | 4008624 | 91 | Sam C Weir | Northern District | 2021/2022 | AW Green Shield | 1 | 1 | Western Suburbs |
| 9 | 91 | 199690 | 155 | 268 | 3958798 | 91 | Jack D Shelley | Northern District | 2021/2022 | Second Grade | 3 | 1 | Hawkesbury |
| 10 | 86 | 761484 | 155 | 268 | 3957578 | 86 | Lachlan D Shaw | Northern District | 2021/2022 | First Grade | 7 | 1 | Gordon |
| 11 | 83 | 676843 | 155 | 268 | 3958790 | 83 | Daniel A Anderson | Northern District | 2021/2022 | Second Grade | 2 | 1 | UNSW |
| 12 | 79 | 662302 | 155 | 268 | 3960235 | 79 | Neil J Kimberley | Northern District | 2021/2022 | Third Grade | 7 | 1 | Gordon |
| 13 | 79 | 1562510 | 155 | 268 | 3963048 | 79 | Brody E Camp | Northern District | 2021/2022 | Fourth Grade | 5 | 1 | Parramatta |
| 14 | 75 | 1247723 | 155 | 268 | 3963079 | 75 | Avinash L Mirando | Northern District | 2021/2022 | Fourth Grade | 8 | 1 | Penrith |
| 15 | 74 | 1940913 | 155 | 268 | 3963048 | 74 | Warren J Saldanha | Northern District | 2021/2022 | Fourth Grade | 5 | 1 | Parramatta |
| 16 | 71 | 700605 | 155 | 268 | 3972623 | 71* | Chris J Green | Northern District | 2021/2022 | Kingsgrove Sports Twenty20 Cup | 1 | 1 | Campbelltown-Camden |
| 17 | 70 | 1474836 | 155 | 268 | 4008913 | 70 | Riley J McDowell | Northern District | 2021/2022 | AW Green Shield | 3 | 1 | Parramatta |
| 18 | 70 | 676843 | 155 | 268 | 3957559 | 70 | Daniel A Anderson | Northern District | 2021/2022 | First Grade | 6 | 1 | Blacktown Mounties |
| 19 | 70 | 679494 | 155 | 268 | 3957578 | 70 | Corey D Miller | Northern District | 2021/2022 | First Grade | 7 | 1 | Gordon |
| 20 | 70 | 676844 | 155 | 268 | 3957422 | 70* | John H Anderson | Northern District | 2021/2022 | First Grade | 5 | 1 | Parramatta |
| 21 | 68 | 965367 | 155 | 268 | 4008624 | 68 | Jordan P Netto | Northern District | 2021/2022 | AW Green Shield | 1 | 1 | Western Suburbs |
| 22 | 67 | 963345 | 155 | 268 | 3963876 | 67 | Krish H Thakur | Northern District | 2021/2022 | Fifth Grade | 9 | 1 | Mosman |
| 23 | 66 | 1035205 | 155 | 268 | 3963856 | 66 | Peter J Murray | Northern District | 2021/2022 | Fifth Grade | 7 | 1 | Gordon |
| 24 | 66 | 976912 | 155 | 268 | 3963817 | 66 | Jack M Slater | Northern District | 2021/2022 | Fifth Grade | 3 | 1 | Hawkesbury |
| 25 | 66 | 798245 | 155 | 268 | 3960224 | 66 | Anthony S Bartlett | Northern District | 2021/2022 | Third Grade | 6 | 1 | Blacktown Mounties |
| 26 | 65 | 661271 | 155 | 268 | 3957315 | 65 | Scott A Rodgie | Northern District | 2021/2022 | First Grade | 4 | 1 | Sydney University |
| 27 | 63 | 675035 | 155 | 268 | 3958837 | 63 | Axel M Cahlin | Northern District | 2021/2022 | Second Grade | 7 | 1 | Gordon |
| 28 | 58 | 800695 | 155 | 268 | 3960215 | 58 | William P Coffey | Northern District | 2021/2022 | Third Grade | 5 | 1 | Parramatta |
| 29 | 58 | 676843 | 155 | 268 | 3957671 | 58 | Daniel A Anderson | Northern District | 2021/2022 | First Grade | 9 | 1 | Mosman |
| 30 | 56 | 234992 | 155 | 268 | 3960188 | 56* | Adam J Wigglesworth | Northern District | 2021/2022 | Third Grade | 2 | 1 | UNSW |
| 31 | 56 | 120385 | 155 | 268 | 3958857 | 56 | Danul N Dassanayake | Northern District | 2021/2022 | Second Grade | 9 | 1 | Mosman |
| 32 | 56 | 661986 | 155 | 268 | 3958817 | 56* | Jonathan I Whealing | Northern District | 2021/2022 | Second Grade | 5 | 1 | Parramatta |
| 33 | 55 | 687467 | 155 | 268 | 3958857 | 55 | Jordan W Fullagar | Northern District | 2021/2022 | Second Grade | 9 | 1 | Mosman |
| 34 | 54 | 234992 | 155 | 268 | 3958863 | 54 | Adam J Wigglesworth | Northern District | 2021/2022 | Second Grade | 10 | 1 | Fairfield-Liverpool |
| 35 | 54 | 761484 | 155 | 268 | 3957297 | 54* | Lachlan D Shaw | Northern District | 2021/2022 | First Grade | 3 | 1 | Hawkesbury |
| 36 | 54 | 676844 | 155 | 268 | 3958798 | 54 | John H Anderson | Northern District | 2021/2022 | Second Grade | 3 | 1 | Hawkesbury |
| 37 | 54 | 976912 | 155 | 268 | 4008624 | 54 | Jack M Slater | Northern District | 2021/2022 | AW Green Shield | 1 | 1 | Western Suburbs |
| 38 | 53 | 1611572 | 155 | 268 | 3995456 | 53 | Megan Chinniah | Northern District | 2021/2022 | U18 Brewer Shield | 5 | 1 | Universities |
| 39 | 53 | 798245 | 155 | 268 | 3963029 | 53 | Anthony S Bartlett | Northern District | 2021/2022 | Fourth Grade | 3 | 1 | Hawkesbury |
| 40 | 53 | 675035 | 155 | 268 | 3958826 | 53 | Axel M Cahlin | Northern District | 2021/2022 | Second Grade | 6 | 1 | Blacktown Mounties |
| 41 | 52 | 661271 | 155 | 268 | 3957680 | 52 | Scott A Rodgie | Northern District | 2021/2022 | First Grade | 10 | 1 | Fairfield-Liverpool |
| 42 | 52 | 662305 | 155 | 268 | 3957680 | 52 | David A Lowery | Northern District | 2021/2022 | First Grade | 10 | 1 | Fairfield-Liverpool |
| 43 | 52 | 1043117 | 155 | 268 | 3958777 | 52 | Jayden C Camp | Northern District | 2021/2022 | Second Grade | 1 | 1 | Manly-Warringah |
| 44 | 52 | 685865 | 155 | 268 | 3960215 | 52 | Mitchell W Crayn | Northern District | 2021/2022 | Third Grade | 5 | 1 | Parramatta |
| 45 | 51 | 662302 | 155 | 268 | 3960261 | 51 | Neil J Kimberley | Northern District | 2021/2022 | Third Grade | 10 | 1 | Fairfield-Liverpool |
| 46 | 51 | 685865 | 155 | 268 | 3960188 | 51* | Mitchell W Crayn | Northern District | 2021/2022 | Third Grade | 2 | 1 | UNSW |
| 47 | 51 | 888555 | 155 | 268 | 3963021 | 51 | Nicholas W Hook | Northern District | 2021/2022 | Fourth Grade | 2 | 1 | UNSW |
| 48 | 51 | 965359 | 155 | 268 | 3958863 | 51 | Cameron W Tunks | Northern District | 2021/2022 | Second Grade | 10 | 1 | Fairfield-Liverpool |
| 49 | 51 | 965838 | 155 | 268 | 3958837 | 51* | Spencer F White | Northern District | 2021/2022 | Second Grade | 7 | 1 | Gordon |
| 50 | 50 | 798245 | 155 | 268 | 3960235 | 50 | Anthony S Bartlett | Northern District | 2021/2022 | Third Grade | 7 | 1 | Gordon |
| 51 | 50 | 662305 | 155 | 268 | 3957297 | 50 | David A Lowery | Northern District | 2021/2022 | First Grade | 3 | 1 | Hawkesbury |
| 52 | 50 | 879100 | 155 | 268 | 3963094 | 50* | Sam C Weir | Northern District | 2021/2022 | Fourth Grade | 10 | 1 | Fairfield-Liverpool |
| 53 | 50 | 966631 | 155 | 268 | 3963809 | 50* | Pat D Murton | Northern District | 2021/2022 | Fifth Grade | 2 | 1 | UNSW |
Note: Qualification levels for this report are 50 and 100 runs.
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